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Visual Studio 2010 is a very good choice for developing portable Client-Side HTML5 and JavaScript applications for Mobile and Desktop.
While Visual Studio 2010 supports JavaScript intellisense there are some tips and tricks you need to know.
Here we go:
Tip 0: Download and install the following Visual Studio 2010 Extensions
Tip1 : If you want to develop client-side application with HTML 5 and JavaScript, start a blank solution and add HTML files and JS files accordingly. Otherwise start and empty WebSite.
Tip2: You may want to use JQuery. To get intellisense for JQuery have a look here.